Flu is a viral infection which usually causes mild symptoms like cough and fever. Children with underlying conditions who develop flu, are at greater ‘at risk’ of becoming unwell from further infections than otherwise healthy children. The ARCHIE Programme will investigate five aspects of the early use of antibiotics in 'at risk' children with flu.

The ARCHIE study will help us find out whether giving ‘at risk’ children antibiotics within the first 5 days of developing flu will reduce the chances of them becoming more unwell or developing further infections.  The ARCHIE study will also help us find out which children are most likely to benefit from antibiotics.

We hope to get 650 children to take part in our study. 

We have GP surgeries and Hospital Trusts around England participating in the ARCHIE Study.  Please find your local participating site using our map below.

We will follow up some ARCHIE study participants for up to a year to find out whether antibiotics would be effective at treating similar infections in future. 

The ARCHIE study is funded by the National Institute for Health Research (NIHR) under its Programme Grants for Applied Research Programme (Grant Reference RP-PG-1210-12012).

Wymondham Medical Centre, Beccles Medical Centre, Orchard Surgery (Dereham), Trinity and Bowthorpe Medical Practice (Norwich) and Oak Street Medical Practice (Norwich) are all taking part in this project. If you are registered at one of these practices and would like more information about the ARCHIE study please speak to your GP or nurse practitioner.