PRIMROSE Study

Prediction and management of cardiovascular disease risk for people with severe mental illnesses: A research programme and trial in primary care (PRIMROSE), which aimed to evaluate the effects of primary care intervention on decreasing total cholesterol concentrations and cardiovascular disease risk in people with severe mental illnesses, findings have been published in The Lancet (Jan 2018).

People with severe mental illnesses have an increased risk of morbidity and mortality from cardiovascular disease compared with the general population.

This health inequality has been recognised for many years but the latest evidence suggests that the mortality gap continues to widen, partly because gains from primary prevention in the general population have not been observed to the same degree in people with severe mental illnesses.

The PRIMROSE trial aimed to evaluate the effects of primary care intervention on decreasing total cholesterol concentrations and cardiovascular disease risk in people with severe mental illnesses.

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